Not to get this thread back on topic or anything, but there is a laundromat on 5th Avenue between (I think) 3rd and 4th Streets, which I believe is open late, although not 24 hours.
That reminds me: The first night I ever spent in New York City was in an apartment above that laundromat. The date was December 30th 1997. Aw, you just have to use it, Tony, it's special.